Jie Du Selected Research

1,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)

1/2022	Artificial Intelligence Uncovers Natural MMP Inhibitor Crocin as a Potential Treatment of Thoracic Aortic Aneurysm and Dissection.
1/2021	Evaluating the monogenic contribution and genotype-phenotype correlation in patients with isolated thoracic aortic aneurysm.
10/2020	Exaggerated Autophagy in Stanford Type A Aortic Dissection: A Transcriptome Pilot Analysis of Human Ascending Aortic Tissues.
1/2018	Interleukin-3 stimulates matrix metalloproteinase 12 production from macrophages promoting thoracic aortic aneurysm/dissection.
11/2017	Clinical Parameters and Gut Microbiome Changes Before and After Surgery in Thoracic Aortic Dissection in Patients with Gastrointestinal Complications.
6/2017	ER stress dependent microparticles derived from smooth muscle cells promote endothelial dysfunction during thoracic aortic aneurysm and dissection.
10/2016	Sustained activation of ADP/P2ry12 signaling induces SMC senescence contributing to thoracic aortic aneurysm/dissection.
7/2015	Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection.

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Jie Du Research Topics

Disease

75	Inflammation (Inflammations) 01/2022 - 06/2005
51	Fibrosis (Cirrhosis) 01/2022 - 12/2009
40	Neoplasms (Cancer) 04/2022 - 01/2004
22	Hypertension (High Blood Pressure) 02/2022 - 09/2006
16	Heart Failure 01/2022 - 09/2010
15	Cardiomegaly (Heart Hypertrophy) 01/2022 - 09/2010
15	Myocardial Infarction 01/2022 - 02/2011
12	Cardiovascular Diseases (Cardiovascular Disease) 07/2022 - 09/2006
12	Hypoxia (Hypoxemia) 01/2022 - 01/2013
12	Hypertrophy 01/2022 - 10/2011
12	Chronic Renal Insufficiency 01/2021 - 06/2004
10	Colitis 11/2021 - 09/2013
10	Abdominal Aortic Aneurysm 01/2021 - 01/2012
9	Body Weight (Weight, Body) 02/2021 - 05/2011
9	Neoplasm Metastasis (Metastasis) 01/2019 - 04/2013
8	Thoracic Aortic Aneurysm 10/2022 - 07/2015
8	Infections 10/2022 - 02/2012
8	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2005
8	Thoracic Aorta Dissection 12/2020 - 01/2016
8	Heart Diseases (Heart Disease) 06/2019 - 10/2013
8	Insulin Resistance 06/2018 - 01/2004
8	Muscular Atrophy (Muscle Atrophy) 05/2011 - 06/2004
7	Rupture 01/2022 - 07/2015
7	Oral Lichen Planus 01/2022 - 01/2018
7	Atherosclerosis 12/2021 - 11/2007
7	Aortic Dissection 01/2021 - 01/2016
7	Reperfusion Injury 08/2016 - 03/2011
6	Ureteral Obstruction 11/2020 - 10/2010
6	Diabetes Mellitus 01/2020 - 06/2006
6	Ischemia 03/2016 - 03/2011
5	Stomach Neoplasms (Stomach Cancer) 11/2022 - 01/2018
5	Coronary Artery Disease (Coronary Atherosclerosis) 12/2021 - 08/2013
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2021 - 11/2014
5	Necrosis 01/2021 - 01/2013
5	ST Elevation Myocardial Infarction 01/2021 - 01/2015
5	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021 - 01/2013
5	Cardiomyopathies (Cardiomyopathy) 01/2021 - 10/2015
5	Thrombosis (Thrombus) 01/2020 - 01/2013
5	Vascular Remodeling 01/2019 - 03/2013
5	Colonic Neoplasms (Colon Cancer) 01/2019 - 11/2014
5	Neointima 10/2015 - 08/2007
4	Acute Coronary Syndrome 11/2021 - 03/2011
4	Vitamin D Deficiency 11/2021 - 11/2017
4	Vascular Calcification 01/2021 - 01/2012
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021 - 02/2015
4	Carcinogenesis 01/2021 - 11/2016

Drug/Important Bio-Agent (IBA)

38	Angiotensin IIIBA 01/2022 - 02/2005
35	Proteins (Proteins, Gene)FDA Link 02/2022 - 01/2005
28	CytokinesIBA 01/2022 - 08/2002
23	MicroRNAs (MicroRNA)IBA 04/2022 - 02/2012
21	CollagenIBA 01/2021 - 06/2011
18	Biomarkers (Surrogate Marker)IBA 07/2022 - 03/2006
16	Vitamin D FDA LinkGeneric 01/2022 - 01/2013
12	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2022 - 09/2013
12	Glucose (Dextrose)FDA LinkGeneric 02/2021 - 06/2006
11	Interleukin-6 (Interleukin 6)IBA 01/2021 - 06/2005
10	UbiquitinIBA 06/2022 - 01/2004
10	Pharmaceutical PreparationsIBA 01/2022 - 04/2014
10	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2015 - 01/2004
8	Small Interfering RNA (siRNA)IBA 01/2022 - 10/2011
8	1,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)IBA 01/2022 - 07/2015
8	Insulin (Novolin)FDA Link 01/2022 - 06/2004
8	LipopolysaccharidesIBA 10/2021 - 01/2013
8	Messenger RNA (mRNA)IBA 01/2021 - 07/2010
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2022 - 08/2002
7	LigandsIBA 07/2022 - 11/2003
7	AminopropionitrileIBA 01/2022 - 07/2015
7	Caspase 3 (Caspase-3)IBA 01/2021 - 01/2004
7	cathepsin SIBA 06/2020 - 01/2012
7	NF-kappa B (NF-kB)IBA 02/2019 - 11/2003
6	EnzymesIBA 10/2022 - 08/2002
6	AcidsIBA 02/2022 - 09/2013
6	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2022 - 01/2011
6	DNA (Deoxyribonucleic Acid)IBA 11/2021 - 01/2019
6	oxidized low density lipoproteinIBA 11/2021 - 12/2003
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 03/2015
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2011
6	RNA (Ribonucleic Acid)IBA 10/2020 - 02/2012
6	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2019 - 06/2011
6	ChemokinesIBA 01/2018 - 03/2014
5	InterferonsIBA 01/2022 - 08/2002
5	Amino Acids FDA Link 01/2021 - 12/2007
5	Peptides (Polypeptides)IBA 01/2021 - 04/2013
5	Complement System Proteins (Complement)IBA 01/2018 - 06/2014
5	Muscle Proteins (Muscle Protein)IBA 05/2011 - 01/2004
4	Floxuridine (FUdR)FDA LinkGeneric 02/2022 - 01/2020
4	SaltsIBA 02/2022 - 09/2010
4	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 01/2013
4	AdiponectinIBA 02/2021 - 12/2007
4	LipidsIBA 01/2021 - 12/2007
4	Bleomycin (Blenoxane)FDA LinkGeneric 01/2021 - 02/2015
4	ElastinIBA 01/2021 - 03/2014
4	Biological ProductsIBA 01/2021 - 01/2012
4	Interleukin-17 (Interleukin 17)IBA 04/2020 - 08/2014
4	CateninsIBA 01/2020 - 05/2013

Therapy/Procedure

29	Therapeutics 02/2022 - 02/2011
9	Drug Therapy (Chemotherapy) 11/2022 - 03/2015
4	Transplantation 01/2022 - 01/2016
4	Radiotherapy 11/2021 - 01/2015
4	Percutaneous Coronary Intervention 01/2021 - 10/2018